Deirdre (Natascha McElhone) puts together a team of experts that she tasks with stealing a valuable briefcase, the contents of which are a mystery. The international team includes Sam (Robert De Niro), an ex-intelligence officer, along with Vincent (Jean Reno), Gregor (Stellan Skarsgard) and others. As their operation gets underway, several team members are found to be untrustworthy, and everyone must complete the mission with a watchful eye on everyone else.
After getting a green card in exchange for assassinating a Cuban government official, Tony Montana (Al Pacino) stakes a claim on the drug trade in Miami. Viciously murdering anyone who stands in his way, Tony eventually becomes the biggest drug lord in the state, controlling nearly all the cocaine that comes through Miami. But increased pressure from the police, wars with Colombian drug cartels and his own drug-fueled paranoia serve to fuel the flames of his eventual downfall.